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Updated: Dec 14, 2025

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Electroretinogram Recording for Infants and Children under Anesthesia to Achieve Optimal Dark Adaptation and International Standards
Published on: September 3, 2020
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Dark without pressure retinal changes in a paediatric age group.
Mariana A Flores Pimentel1, Jacque L Duncan1, Alejandra G de Alba Campomanes1
1Department of Opthalmology, University of California, san Francisco, 10 Koret Way, San Francisco, CA, 94143-0730, USA.
Eye (London, England)
|July 22, 2020
Summary
Dark without pressure (DWP) lesions in young children share similar clinical and imaging features with adults. These outer retinal findings are benign and do not resolve, preventing unnecessary patient anxiety.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Retinal Imaging
Background:
- Dark without pressure (DWP) is a retinal finding characterized by a dark area in the mid-periphery.
- Associated imaging findings include attenuated hyperreflective outer segment bands on spectral domain OCT.
- This study focuses on DWP in young children.
Purpose of the Study:
- To describe the clinical and imaging characteristics of DWP in young children.
- To compare findings in children with those previously reported in adults.
Main Methods:
- Retrospective review of medical charts and retinal images.
- Inclusion criteria: children with DWP seen in a pediatric eye clinic.
- Imaging modalities included fundus autofluorescence and spectral domain OCT.
Main Results:
- Six children aged 3-13 years with DWP lesions were identified.
- Lesions were incidental findings, located in the mid-peripheral retina, sparing the macula.
- Imaging revealed hypoautofluorescence and reduced outer segment/EZ line reflectivity, consistent with adult findings.
Conclusions:
- DWP in young children exhibits similar characteristics to those in adults.
- The dysfunction is located in the outer retina, but the etiology remains unknown.
- Recognizing DWP as a benign condition can alleviate patient anxiety and avoid further investigations.

