Related Experiment Video
Updated: Dec 14, 2025
08:45
New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
Published on: June 27, 2025
1.2K
An Update on the Management of Budd-Chiari Syndrome
A Sharma1, S N Keshava2, A Eapen3
1Hepatology Department, Christian Medical College, Vellore, Tamil Nadu, India.
Digestive Diseases and Sciences
|July 22, 2020
Summary
Budd-Chiari syndrome (BCS), a rare hepatic venous outflow obstruction, is often underdiagnosed. Myeloproliferative neoplasms are the most common cause, with improved diagnosis and endovascular treatments enhancing patient survival.
Area of Science:
- Hepatology
- Vascular Medicine
- Hematology
Background:
- Budd-Chiari syndrome (BCS) is an uncommon condition characterized by hepatic venous outflow obstruction.
- It is frequently underdiagnosed, necessitating a high index of suspicion in patients with unexplained portal hypertension.
Purpose of the Study:
- To review the current understanding of Budd-Chiari syndrome (BCS) etiology, pathology, diagnosis, and management.
- To highlight recent advances and discuss unresolved issues in BCS treatment.
Main Methods:
- Literature review focusing on recent studies and diagnostic techniques.
- Analysis of current treatment modalities including endovascular interventions, anticoagulation, and liver transplantation.
- Discussion of the role of genetic studies in diagnosing underlying myeloproliferative neoplasms (MPN).
Main Results:
- Identifiable etiologies are found in over 80% of BCS cases, with myeloproliferative neoplasm (MPN) being the most frequent.
- Advances in cross-sectional imaging improve the accuracy of obstruction site delineation.
- Endovascular interventions and anticoagulation have significantly improved survival rates for BCS patients.
Conclusions:
- Early diagnosis of BCS, particularly in patients with unexplained portal hypertension and potential MPN, is crucial.
- Endovascular angioplasty for hepatic veins/inferior vena cava is underutilized but effective.
- Current management strategies focus on endovascular treatments and anticoagulation, with liver transplantation reserved for specific indications.
Related Concept Videos
01:28Esophageal Varices-II: Clinical Features and Management
279
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
279
01:29Chronic Pancreatitis II: Collaborative Care
206
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
206
01:17Chronic Bowel Disorders: Introduction
676
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
676
01:29Venous Thrombosis III: Interprofessional Care
189
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
189
01:30Venous Thrombosis IV: Nursing Management
138
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
138
01:26Mitral Stenosis III: Medical Management
155
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
155