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Plasmonic tweezers for optical manipulation and biomedical applications
Hongtao Tan1, Huiqian Hu, Lin Huang
1Department of Pancreatobiliary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, 150001, P. R. China.
The Analyst
|July 22, 2020
Summary
Plasmonic tweezers enable nanoscale manipulation beyond the diffraction limit. Their integration with analytical methods promises advancements in bioanalysis and biological detection for research and industry.
Area of Science:
- Nanotechnology
- Biophysics
- Analytical Chemistry
Background:
- Plasmonic tweezers overcome conventional diffraction limits for nanoscale manipulation.
- They are compatible with analytical techniques like SERS and LDI MS.
- This compatibility enables novel optical manipulation and biomedical applications.
Purpose of the Study:
- To review the structures, trapping forces, and properties of plasmonic tweezers.
- To summarize the optical trapping of various biosamples, including microorganisms and biomolecules.
- To highlight the integration of plasmonic tweezers with analytical techniques for bioanalytical applications.
Main Methods:
- Review of plasmonic tweezer structures and trapping forces.
- Summary of plasmonic tweezer properties.
- Compilation of studies on optical trapping of biosamples.
- Analysis of plasmonic tweezer integration with analytical techniques.
Main Results:
- Plasmonic tweezers offer precise nanoscale manipulation capabilities.
- They facilitate the optical trapping of diverse biological entities.
- Integration with analytical techniques enhances bioanalytical potential.
Conclusions:
- Plasmonic tweezers are a key technology for advanced bioanalysis.
- Future research directions point towards an era of plasmonic detection in academia and industry.
- Interdisciplinary collaboration is crucial for advancing this field.
