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Updated: Dec 14, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
Vertical transmission of SARS CoV-2: a systematic review
1Department of Pediatric Infectious Diseases, Faculty of Medicine, Gazi University, Ankara, Turkey.
Objective:
The aim of this study is to review the current evidence on the vertical transmission of SARS CoV-2.
Methods:
Combination of the following keywords; COVID-19, SARS CoV-2, placenta, vertical transmission, intrauterine infection, breast milk were searched in databases.
Results:
In the 50 studies included, 17 newborns testing positive for SARS CoV-2 by RT-PCR were reported. In three neonates, SARS-CoV-2 IgG and IgM levels were elevated. Eight placental tissues testing positive for the virus were reported. Three positive RT-PCR results of test of breast milk have been reported recently. One amniotic fluid testing positive was reported.
Conclusion:
Possible vertical transmission of SARS CoV-2 has been observed in some studies currently. More RT-PCR tests on amniotic fluid, placenta, breast milk and cord blood are required.
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