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Updated: Jul 6, 2026

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies

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Precision Detection Technology: Equipping Precision Oncology with Wings.

Rilan Bai¹, Zheng Lv¹, Xiao Chen¹

¹Cancer Center, The First Hospital of Jilin University, Changchun, Jilin 130021, China.

Journal of Oncology

|July 23, 2020

Summary

This summary is machine-generated.

Precision medical detection has advanced from low-throughput to high-throughput genomic sequencing and single-cell analysis. Liquid biopsy offers a significant improvement over traditional tissue biopsy for disease monitoring and drug development.

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Area of Science:

Genomics
Molecular Biology
Oncology

Background:

Precision medicine relies on advanced detection techniques for accurate diagnostics and treatment.
Traditional tissue biopsy has limitations in accessibility and invasiveness.
Genomic sequencing has evolved from low-throughput to high-throughput and single-cell resolution.

Purpose of the Study:

To review the evolution of precision medical detection technologies.
To discuss the development and clinical applications of liquid biopsy.
To highlight future challenges and opportunities in precision detection.

Main Methods:

Review of recent advancements in genomic sequencing (low-throughput to high-throughput, multicell to single-cell).
Analysis of the emergence and impact of liquid biopsy technology.
Exploration of the role of precision detection in disease monitoring and therapeutic evaluation.

Main Results:

Precision detection has transformed from low-throughput to high-throughput and single-cell sequencing.
Liquid biopsy overcomes limitations of tissue biopsy, enabling significant advancements in precision detection.
Precision techniques enhance disease monitoring, therapeutic evaluation, and drug development.

Conclusions:

Liquid biopsy represents a major transformation in precision medical detection.
Future research should focus on integrating precision detection in epigenetics, rare gene analysis, and combination therapies.
Continued exploration of precision detection is crucial for personalized medicine advancements.