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Related Experiment Video

Updated: Dec 14, 2025

Author Spotlight: Cutting-Edge Robotic Heller Myotomy Protocol for Treatment of Achalasia
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Persistent Postoperative Hiccups.

Emily Bryer1, Jeffrey Bryer2

  • 1Department of Internal Medicine, Pennsylvania Hospital, Pennsylvania, PA, USA.

Case Reports in Anesthesiology
|July 23, 2020
PubMed
Summary

Persistent hiccups can be a concerning symptom, sometimes indicating serious underlying conditions like pulmonary embolism. This case highlights gastroesophageal reflux disease as a potential cause following surgery.

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Area of Science:

  • Neurology
  • Gastroenterology
  • Pulmonology

Background:

  • Hiccups are a common, yet poorly understood, involuntary diaphragmatic spasm.
  • Persistent hiccups lasting weeks or months lack sufficient data on etiology and treatment.
  • While often benign, hiccups can signal serious conditions such as cardiac disease or pulmonary embolism.

Observation:

  • A patient developed 11 days of recurrent hiccups post-orthopedic procedure.
  • The patient had a history of gastroesophageal reflux disease (GERD).

Findings:

  • The case suggests a potential link between gastroesophageal reflux disease and persistent hiccups after surgery.
  • This highlights the importance of considering GERD in the differential diagnosis of post-procedural hiccups.

Implications:

  • Further research is needed to understand the relationship between GERD and persistent hiccups.
  • Clinicians should consider GERD in patients presenting with prolonged hiccups, especially post-operatively.
  • This case underscores the need for comprehensive evaluation of persistent hiccups beyond viewing them as merely benign.