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Updated: Dec 14, 2025

Real Time Monitoring of Intracellular Bile Acid Dynamics Using a Genetically Encoded FRET-based Bile Acid Sensor
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Structural basis of GPBAR activation and bile acid recognition

Fan Yang1,2, Chunyou Mao3,4, Lulu Guo1,2

  • 1Key Laboratory Experimental Teratology of the Ministry of Education, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, China.

Nature
|July 23, 2020
PubMed
Summary

Structural insights into the G-protein-coupled bile acid receptor (GPBAR) reveal unique features for bile acid recognition and signaling. These findings illuminate the receptor

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