Related Experiment Video

Updated: Dec 14, 2025

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

1.3K

Kidney disease and electrolytes in COVID-19: more than meets the eye

Sol Carriazo1, Mehmet Kanbay2, Alberto Ortiz1

  • 1IIS-Fundación Jiménez Diaz UAM and School of Medicine, Universidad Autonoma de Madrid, Madrid, Spain.

Clinical Kidney Journal
|July 24, 2020
PubMed

Insights

This review covers the global impact of COVID-19 on kidney disease, highlighting acute kidney injury and cardiorenal syndromes. It discusses dialysis options, risks for chronic kidney disease patients, and emerging therapies.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Public Health

Background:

  • COVID-19 pandemic significantly impacts global health, with government actions influencing its spread.
  • Kidney disease is a major complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
  • The Clinical Kidney Journal issue compiles research from three continents on COVID-19's renal manifestations.

Discussion:

  • Clinical presentations include SIADH, AKI, CKD, collapsing glomerulopathy, and thrombotic microangiopathy.
  • Acute kidney injury management challenges, including hemodialysis (HD) and hemofiltration capacity.
  • Acute peritoneal dialysis (PD) as a critical life-saving intervention.

Key Insights:

  • Pre-existing chronic kidney disease (CKD) elevates COVID-19 complication risk.
  • Impact of COVID-19 on patients undergoing PD and HD, with emphasis on prevention.
  • Review of current and investigational therapies, including complement inhibition (eculizumab).

Outlook:

  • Further research into novel therapeutic strategies for COVID-19-related kidney disease.
  • Potential for eculizumab and other complement inhibitors in clinical trials.
  • Importance of global collaboration in understanding and managing renal complications of COVID-19.

Keywords:
APOL1COVID-19FanconiSIADHacute kidney injurycardiorenalchronic kidney diseasehaemodialysisperitoneal dialysis

More Related Videos

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice10:31

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Published on: May 2, 2025

512
A Mouse 5/6th Nephrectomy Model That Induces Experimental Uremic Cardiomyopathy07:52

A Mouse 5/6th Nephrectomy Model That Induces Experimental Uremic Cardiomyopathy

Published on: November 7, 2017

21.6K

Related Concept Videos

Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
246
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
427
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
181
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
190
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
198
Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
264