Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pediatric cerebral abscess.

S D Moss1, D G McLone, M Arditi

  • 1Department of Neurological Surgery, Northwestern University, Children's Memorial Hospital, Chicago, Ill.

Pediatric Neuroscience
|January 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

IL-1-dependent electrophysiological changes and cardiac neural remodeling in a mouse model of Kawasaki disease vasculitis.

Clinical and experimental immunology·2019
Same author

IL-1 receptor antagonist, anakinra, prevents myocardial dysfunction in a mouse model of Kawasaki disease vasculitis and myocarditis.

Clinical and experimental immunology·2019
Same author

Sonothrombolysis: the contribution of stable and inertial cavitation to clot lysis.

Ultrasound in medicine & biology·2015
Same author

Ultrasound contrast agents for ultrasound molecular imaging.

Zeitschrift fur Gastroenterologie·2014
Same author

Use of opportunistic clinical data and a population pharmacokinetic model to support dosing of clindamycin for premature infants to adolescents.

Clinical pharmacology and therapeutics·2014
Same author

The role of pattern recognition receptors in intestinal inflammation.

Mucosal immunology·2013
Same journal

2nd annual International Symposium on Pediatric Neuro-Oncology. Philadelphia, Pa, May 24-26, 1990. Abstracts.

Pediatric neuroscience·1989
Same journal

Intracranial lymphoblastic sarcoma mimicking a primary brain tumor.

Pediatric neuroscience·1989
Same journal

Delayed cerebrospinal-fluid shunt infection in children.

Pediatric neuroscience·1989
Same journal

Candida albicans shunt infection.

Pediatric neuroscience·1989
Same journal

Intrauterine depressed skull fracture. A report of two cases.

Pediatric neuroscience·1989
Same journal

Cerebrospinal fluid shunt infections. Report of 41 cases and a critical review of the literature.

Pediatric neuroscience·1989
See all related articles

Pediatric cerebral abscesses are complex, with varied causes and treatments. Surgical intervention, particularly resection or evacuation, significantly improves outcomes compared to aspiration, with CT scans enhancing diagnosis and reducing mortality.

Area of Science:

  • Pediatric Neurosurgery
  • Infectious Diseases

Background:

  • Cerebral abscesses in children present a significant neurosurgical challenge.
  • Historical treatment approaches varied, impacting patient outcomes.

Observation:

  • A review of 54 pediatric cerebral abscess cases from 1958-1987 revealed diverse etiologies, including cyanotic heart disease, hydrocephalus/shunt infections, sinusitis, otitis, and tuberculomas.
  • Organisms identified included streptococci (26%), staphylococci (9%), and fungi (7%), with 26% of cultures remaining negative.
  • Underlying conditions were absent in 19% of cases.

Findings:

  • Surgical resection or evacuation of cerebral abscesses demonstrated lower mortality rates (7-9%) compared to aspiration (17%).
  • Patient's clinical status on admission was the strongest predictor of mortality.

Related Experiment Videos

  • The introduction of CT scanning dramatically reduced overall mortality from 31% to 5.7% and surgical mortality from 21% to 2.9%.

    • Implications:

    • Aggressive surgical management, especially resection and evacuation, is crucial for improving survival in pediatric cerebral abscess.
    • Early diagnosis and intervention, facilitated by advanced imaging like CT scans, are vital for reducing morbidity and mortality.
    • Understanding the diverse etiologies and risk factors is essential for tailored treatment strategies in pediatric neurosurgery.