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Postradiation meningioma in a child
C Balasubramaniam1, D Armstrong, W Cheek
1Neurosurgery Service, Texas Children's Hospital, Baylor College of Medicine, Houston.
Summary
Postradiation meningiomas (PRM) are distinct tumors that can arise years after radiation therapy. This case highlights a pediatric PRM with unusual subdural hematoma membrane attachment, not involving the dura.
Area of Science:
- Neuro-oncology
- Pediatric oncology
- Radiation oncology
Background:
- Radiation therapy is a known risk factor for secondary tumors, including meningiomas.
- Postradiation meningiomas (PRM) are recognized as a distinct clinicopathological entity.
- Meningiomas in children are rare and their association with prior radiation warrants specific attention.
Observation:
- A pediatric case of a postradiation meningioma (PRM) is presented.
- The patient received radiation therapy 11 years prior for a presumed thalamic glioma.
- The PRM exhibited an unusual attachment to the membrane of a pre-existing subdural hematoma, lacking dural attachment.
Findings:
- This case illustrates a rare instance of pediatric PRM.
- The tumor's unique adherence to subdural hematoma membranes, bypassing dural attachment, is noteworthy.
- Pathological features of PRMs and pediatric meningiomas are discussed in the context of this case.
Implications:
- Understanding PRM development is crucial for long-term surveillance in pediatric patients treated with radiation.
- The atypical attachment highlights the diverse biological behavior and growth patterns of PRMs.
- This case contributes to the understanding of meningioma pathology in children, particularly those with a history of radiation exposure.