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Gender Correlation to the Prevalence of Pedal Neuromas in Various Interspaces - A Retrospective Study
Journal of the American Podiatric Medical Association
|July 24, 2020
Summary
Morton's neuroma location, age, and laterality do not significantly differ between genders. However, males with Morton's neuroma showed a higher incidence of plantar plate tears.
Area of Science:
- Podiatric Medicine
- Radiology
- Orthopedic Surgery
Background:
- Morton's neuroma is a common digital nerve abnormality.
- Historically, it was thought to be more prevalent in women and in the third interspace.
- This study challenges traditional views by examining gender-specific variations in neuroma location.
Purpose of the Study:
- To evaluate the interspace location of Morton's neuromas.
- To determine if Morton's neuroma location varies between males and females.
- To investigate gender-specific differences in associated factors like plantar plate tears.
Main Methods:
- Retrospective analysis of 379 MRI reports for Morton's neuroma (ICD Code 355.6).
- Data collected included gender, age, laterality, trauma history, and interspace location (focus on 2nd and 3rd).
- Statistical analysis using Pearson Chi-Square and Mann-Whitney U tests (p<0.05).
Main Results:
- No significant gender-based differences in Morton's neuroma location (2nd vs. 3rd interspace).
- Age, laterality, and history of trauma did not significantly vary between genders.
- A statistically significant higher rate of plantar plate tears was observed in males (p=0.01).
Conclusions:
- Morton's neuroma location, laterality, and age distribution are similar in males and females.
- The higher prevalence of plantar plate tears in males warrants further investigation.
- Findings suggest a need to reconsider traditional assumptions about Morton's neuroma demographics.

