Case report of extreme gastric distention and perforation with pathologic Sarcina ventriculi colonization and Rett

Carla M Lopez1, Mark L Kovler1, Eric B Jelin1

  • 1Department of Pediatric Surgery, Johns Hopkins University, Baltimore, MD, United States.

Insights

Rett syndrome patients with extreme air swallowing may develop Sarcina ventriculi gastric perforation. This rare bacterial link highlights a critical diagnostic consideration in affected children.

Area of Science:

  • Pediatric Gastroenterology
  • Microbiology
  • Genetics

Background:

  • Rett syndrome is a neurodevelopmental disorder often associated with gastrointestinal issues.
  • Aerophagia (excessive air swallowing) is a known complication in individuals with intellectual disabilities.
  • Sarcina ventriculi is a rare bacterium linked to gastrointestinal distension and perforation.

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