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Case report of extreme gastric distention and perforation with pathologic Sarcina ventriculi colonization and Rett
Carla M Lopez1, Mark L Kovler1, Eric B Jelin1
1Department of Pediatric Surgery, Johns Hopkins University, Baltimore, MD, United States.
Insights
Rett syndrome patients with extreme air swallowing may develop Sarcina ventriculi gastric perforation. This rare bacterial link highlights a critical diagnostic consideration in affected children.
Area of Science:
- Pediatric Gastroenterology
- Microbiology
- Genetics
Background:
- Rett syndrome is a neurodevelopmental disorder often associated with gastrointestinal issues.
- Aerophagia (excessive air swallowing) is a known complication in individuals with intellectual disabilities.
- Sarcina ventriculi is a rare bacterium linked to gastrointestinal distension and perforation.
Abstract:
Here we describe a case of a 15-year-old child with Rett syndrome who presented with extreme gastric distension and fatal perforation in the setting of long-standing aerophagia and pathologic colonization with Sarcina ventriculi, a rare bacteria implicated in gastric perforation. This is the first report of gastric perforation associated with colonization by Sarcina in a patient with pathologic aerophagia. Gastric colonization with Sarcina should be considered in intellectually disabled children with pathologic air swallowing who present with severe gastric dilation and/or perforation.
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