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Selecting Appropriate Sarcopenia Screening Methods for Asian Populations.

Yu-Ching Lin1,2, Yi-Chien Lu3, Fang-Ping Chen2,4

  • 1Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Keelung and Chang Gung University, Taoyuan 33001, Taiwan.

Journal of Clinical Medicine
|July 26, 2020
PubMed
Summary

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The clinical brake: Restoring conscience to care.

The American journal of medicine·2026
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Pre-teriparatide anti-osteoporosis medication therapy and fracture-related hospitalization in patients at very high fracture risk.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2026
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Consensus statement on the application of artificial intelligence in osteoporosis screening and management: perspectives from the Asia-Pacific region.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2026
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Lumbar spine DXA T-score and QCT BMD cutpoint values for defining osteofrailia among older men: a framework for further refinement.

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Osteoporosis and sarcopenia·2026

Handgrip strength (HS) screening is recommended for sarcopenia in Asian populations. While skeletal muscle mass indices vary by sex, HS provides a more consistent prevalence measure across age groups and genders.

Area of Science:

  • Gerontology
  • Public Health
  • Human Physiology

Background:

  • Sarcopenia screening methods require validation for diverse populations, particularly in Asia.
  • Understanding sex-specific physiological changes with aging is crucial for accurate sarcopenia assessment.

Purpose of the Study:

  • To identify the optimal sarcopenia screening method for Asian populations.
  • To compare skeletal muscle mass indices and handgrip strength (HS) for sarcopenia detection.

Main Methods:

  • Retrospective analysis of sex-based physiological differences.
  • Prospective community-based study comparing dual-energy X-ray absorptiometry (DXA) derived skeletal muscle mass indices (weight-adjusted SMI and height-adjusted SMI) with handgrip strength (HS).

Main Results:

Keywords:
Asianadjusted skeletal muscle indexbody compositiondual-energy X-ray absorptiometry (DXA)handgrip strengthsarcopenia

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  • Skeletal muscle mass declined similarly in both sexes post-peak. Fat mass increased with age in women but declined in men.
  • Prevalence of low skeletal muscle mass increased with age using weight-adjusted SMI (both sexes) and height-adjusted SMI (men only).
  • Handgrip strength (HS) screening indicated a higher sarcopenia prevalence in both sexes compared to muscle mass indices.

Conclusions:

  • Weight-adjusted SMI is more appropriate for women, and height-adjusted SMI for men, considering age-related fat mass changes.
  • A primary handgrip strength (HS) survey is recommended as the most appropriate initial screening tool for sarcopenia in both sexes within Asian populations.