Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stress and Mental Health01:30

Stress and Mental Health

393
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
393
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

247
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
247
Introduction to Stress and Lifestyle01:27

Introduction to Stress and Lifestyle

419
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
419
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

342
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
342
Stress Prevention and Stress Management Techniques IV01:26

Stress Prevention and Stress Management Techniques IV

166
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
166
Psychological Responses to Stress01:20

Psychological Responses to Stress

396
Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
396

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A selective machine learning algorithm for severe periodontitis labeling from questionnaire data.

Scientific reports·2026
Same author

Longitudinal proteomic analysis of GCF in regenerative healing of molar furcation degree II defects treated with OFD, EMD, or A-PRF + : a pilot study.

Scientific reports·2026
Same author

Estimating the Causal Effect of Tooth Loss on the Critical Outcome of COVID-19.

JDR clinical and translational research·2025
Same author

Effects of Advanced Platelet Rich Fibrin (A-PRF+), Enamel Matrix Derivative (EMD) and Open Flap Debridement on clinical and wound healing parameters in molar furcation sites: A case series from a RCT study.

Frontiers in dental medicine·2025
Same author

Attempts to Modify Periodontal Screening Models Based on a Self-Reported Oral Health Questionnaire in the Medical Care Setting.

Journal of clinical periodontology·2024
Same author

[Temporomandibular dysfunction and bruxism in patients with early rheumatoid arthritis and at-risk patients: a cross-sectional study].

Nederlands tijdschrift voor tandheelkunde·2024
Same journal

[Jaw problems and dental occlusion: is further research necessary?]

Nederlands tijdschrift voor tandheelkunde·2026
Same journal

[Dentists and oral care in Dutch-language picture books].

Nederlands tijdschrift voor tandheelkunde·2026
Same journal

[Series: Important medical-dental interactions. Oral manifestations in patients with intestinal diseases].

Nederlands tijdschrift voor tandheelkunde·2026
Same journal

[Indications for and claims to dental specialties: case studies].

Nederlands tijdschrift voor tandheelkunde·2026
Same journal

[Indications for and claims to dental specialties: regulatory framework].

Nederlands tijdschrift voor tandheelkunde·2026
Same journal

[Justification and optimization of intraoral and panoramic radiographs in oral care].

Nederlands tijdschrift voor tandheelkunde·2026
See all related articles

Related Experiment Video

Updated: Dec 13, 2025

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
07:15

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

Published on: January 21, 2020

12.0K

[Stress and periodontitis].

L Pitzurra, B G Loos

    Nederlands Tijdschrift Voor Tandheelkunde
    |July 28, 2020
    PubMed
    Summary
    This summary is machine-generated.

    Stress negatively impacts immune fitness, worsening gum disease like gingivitis and periodontitis. Managing stress is crucial for better periodontal health and treatment outcomes.

    More Related Videos

    Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness
    06:36

    Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness

    Published on: March 14, 2025

    647
    Isolation, Processing and Analysis of Murine Gingival Cells
    09:47

    Isolation, Processing and Analysis of Murine Gingival Cells

    Published on: July 2, 2013

    19.6K

    Related Experiment Videos

    Last Updated: Dec 13, 2025

    Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
    07:15

    Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils

    Published on: January 21, 2020

    12.0K
    Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness
    06:36

    Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness

    Published on: March 14, 2025

    647
    Isolation, Processing and Analysis of Murine Gingival Cells
    09:47

    Isolation, Processing and Analysis of Murine Gingival Cells

    Published on: July 2, 2013

    19.6K

    Area of Science:

    • Oral health
    • Immunology
    • Microbiome research

    Background:

    • Reduced immune fitness disrupts the host-microbiome balance, exacerbating gingivitis and periodontitis.
    • Lifestyle factors such as stress and smoking significantly impair immune fitness.
    • Stress is linked to periodontitis and acute necrotizing ulcerative gingivitis, potentially via neuronal pro-inflammatory mediators.

    Purpose of the Study:

    • To explore the impact of stress on immune fitness and its role in the pathogenesis and treatment of periodontal diseases.
    • To investigate the potential mechanisms by which stress influences the oral microbiome and inflammatory responses in the periodontium.

    Main Methods:

    • Review of existing literature on stress, immune function, and periodontal disease.
    • Analysis of in vitro studies examining the effects of cortisol on oral bacteria like P. gingivalis.
    • Clinical observations and associations between stress, periodontal status, and treatment outcomes.

    Main Results:

    • Stress and smoking are identified as key lifestyle factors that reduce immune fitness and negatively affect periodontal health.
    • Evidence suggests neurons may secrete inflammatory cytokines, worsening chronic periodontitis and compromising immune defenses.
    • In vitro data indicate elevated cortisol levels can promote the growth of P. gingivalis, a key pathogen in periodontitis.

    Conclusions:

    • Stress is a significant, though clinically challenging to quantify, risk factor for periodontitis.
    • Awareness and management of stress are vital components of comprehensive periodontal care to mitigate its detrimental effects on immune fitness and treatment success.