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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

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Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
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Dosage Regimen: Individualization01:24

Dosage Regimen: Individualization

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Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
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Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

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Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
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Related Experiment Video

Updated: Dec 13, 2025

Community-based Adapted Tango Dancing for Individuals with Parkinson's Disease and Older Adults
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Incorporating Pharmacist Interns Into a Study of Fall-Risks.

P Brittany Vickery, Greg Ginn, Stephen B Vickery

    The Senior Care Pharmacist
    |July 29, 2020
    PubMed
    Summary

    Pharmacist interns developed a fall risk scoring metric for hospitalized geriatric and psychiatric patients. The initiative did not significantly reduce falls, and the scoring metric did not correlate with fall incidents.

    Area of Science:

    • Geriatric Medicine
    • Psychiatric Nursing
    • Patient Safety

    Background:

    • Inpatient falls pose significant risks to patient recovery and care.
    • Predicting patient fall risk is complex due to various contributing factors.
    • Student learners can potentially aid in identifying high-risk patients.

    Purpose of the Study:

    • To develop a scoring metric for identifying hospitalized geriatric and medical psychiatric patients at risk of falling.
    • To evaluate the reliability of this scoring metric in a clinical setting.

    Main Methods:

    • A single-center, quasi-experimental study involving pharmacist interns.
    • Implementation of a fall-prevention initiative across two behavioral health units.
    • Analysis of fall data and a developed scoring metric for 96 patients.

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    Main Results:

    • No significant trends in fall rates were observed for geriatric or medical psychiatric patients.
    • The scoring metric did not show a statistically significant correlation with the odds of falling in either patient group.
    • The odds ratio for falling per score increase was 0.95 (CI 0.83-1.08) for geriatric-psychiatric and 1.11 (CI 0.91-1.36) for medical-psychiatric units.

    Conclusions:

    • The pharmacist-intern-led fall-prevention initiative did not achieve a statistically significant reduction in inpatient falls.
    • While the scoring metric assisted in chart reviews and intervention recommendations, it did not accurately predict fall incidents.
    • Further research may be needed to refine fall risk assessment tools in psychiatric and geriatric populations.