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The top 10 cosmeceuticals for facial hyperpigmentation.
Tamara Searle1, Firas Al-Niaimi2, Faisal R Ali3,4
1University of Birmingham Medical School, Birmingham, UK.
Dermatologic Therapy
|July 29, 2020
Summary
Cosmeceuticals offer a promising, safer alternative for treating facial hyperpigmentation like melasma. These products, including thiamidol and vitamin C, target melanin production by inhibiting tyrosinase.
Area of Science:
- Dermatology
- Cosmeceutical Science
Background:
- Facial hyperpigmentation disorders (melasma, postinflammatory hyperpigmentation, solar lentigines) significantly impact quality of life and are challenging to treat.
- Cosmeceutical products are emerging as a potentially safer and effective treatment option.
Purpose of the Study:
- To review the evidence base for the top 10 cosmeceutical products used for hyperpigmentation and melasma.
- To discuss the mode of action of these cosmeceuticals, particularly tyrosinase inhibition.
Main Methods:
- Literature review of cosmeceutical products for hyperpigmentation.
- Analysis of scientific evidence supporting efficacy and safety.
Main Results:
- Identified 10 key cosmeceutical ingredients: thiamidol, kojic acid, vitamin C, arbutin, retinol, nicotinamide, ferulic acid, resorcinol, licorice root extract, and soy.
- Discussed their mechanisms, primarily tyrosinase inhibition in melanogenesis.
Conclusions:
- Cosmeceuticals present a viable therapeutic avenue for hyperpigmentation disorders.
- Further research into these agents can lead to improved treatment strategies.
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