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Italian recommendations on enzymatic debridement in burn surgery
Rosario Ranno1, Michelangelo Vestita2, Giulio Maggio2
1Burn Unit, Ospedale Cannizzaro, Catania, Italy.
Summary
Italian burn surgery experts developed consensus recommendations for enzymatic debridement using Nexobrid®. These guidelines, based on extensive experience, aim to optimize eschar removal in burn wound care.
Area of Science:
- Burn Surgery
- Wound Care
- Enzymatic Debridement
Background:
- Nexobrid®, a bromelain-based enzymatic debridement agent, is increasingly utilized.
- Expert clinical knowledge on its application in burn treatment is valuable.
Purpose of the Study:
- To establish Italian expert consensus recommendations for enzymatic debridement (Nexobrid®) in burn surgery.
- To define the role of enzymatic debridement in eschar removal for burn patients.
Main Methods:
- A multi-phase Delphi method was employed.
- Consensus was sought among Italian burn surgery experts from various centers.
- Experts had significant combined experience with enzymatic debridement.
Main Results:
- 100% consensus was achieved on 26 out of 27 statements after three rounds.
- Full, strong consensus was reached on 24 out of 27 statements.
- The panel comprised experts with 1068 burn patients treated with enzymatic debridement.
Conclusions:
- The developed recommendations offer practical guidance for enzymatic debridement in Italian burn surgery.
- These expert-driven guidelines supplement existing scientific literature.
- The recommendations are intended to be dynamic and will be updated with new evidence.
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