Topical treatment for facial burns

Area of Science:

• Dermatology
• Wound Healing
• Burn Care

Background:

• Facial burns are a significant health concern, impacting identity and communication.
• Topical interventions are the primary treatment for facial burns.

Purpose of the Study:

• To assess the effects of topical interventions on wound healing in individuals with facial burns of any depth.

Main Methods:

• A systematic review of randomized controlled trials (RCTs) was conducted.
• Searches included major databases up to December 2019, with no language or date restrictions.
• Twelve RCTs involving 507 participants were included.

Main Results:

• Evidence for most topical agents (antimicrobials, non-antimicrobials, skin substitutes) is of low to very low certainty.
• Moderate certainty suggests little difference in healing time between antimicrobial and non-antimicrobial agents.
• Uncertainty exists regarding wound infection, scar quality, and patient satisfaction due to limited and low-quality evidence.

Conclusions:

• The current evidence base for topical interventions in facial burn wound healing is largely of low to very low certainty.
• While the number of RCTs is increasing, methodological limitations hinder definitive conclusions.
• Further high-quality research is needed to guide optimal treatment strategies for facial burns.