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Related Experiment Video

Updated: Dec 13, 2025

Utilization of Plasmonic and Photonic Crystal Nanostructures for Enhanced Micro- and Nanoparticle Manipulation
09:29

Utilization of Plasmonic and Photonic Crystal Nanostructures for Enhanced Micro- and Nanoparticle Manipulation

Published on: September 27, 2011

12.6K

Single plasmonic nanostructures for biomedical diagnosis.

Xingyi Ma1, Sang Jun Sim1

  • 1Department of Chemical and Biological Engineering, Korea University, Seoul 02841, Korea. simsj@korea.ac.kr.

Journal of Materials Chemistry. B
|July 30, 2020
PubMed
Summary

Single nanoparticle plasmonics offers powerful tools for biomedical research. These nanoplasmonic biosensors enable label-free detection and real-time monitoring of biomolecules for advanced diagnostics.

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Area of Science:

  • Nanotechnology
  • Biomedical Engineering
  • Optics

Background:

  • Single nanoparticle plasmonics has seen significant growth, offering diverse techniques and nanostructures.
  • Nanoplasmonic applications are crucial for fundamental biomedical studies, sensing, and imaging.
  • Single nanoparticle plasmonic biosensors excel at label-free, single-molecule detection and real-time biomolecule binding event monitoring.

Purpose of the Study:

  • To review advances in single particle characterization and synthesis for nanoplasmonics.
  • To explore new insights into biomedical diagnosis using single particle approaches.
  • To highlight practical applications of single particle sensing, imaging, and tracking.

Main Methods:

  • Fundamental studies of nanoplasmonic behavior.

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Last Updated: Dec 13, 2025

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  • Methods based on refractive index change and characteristic light intensity change.
  • Innovations in synthetic strategies for novel plasmonic nanostructures.

    • Main Results:

    • Demonstration of label-free single-molecule detection using plasmonic biosensors.
    • Real-time monitoring of biomolecule binding events.
    • Development of algorithmic assemblies from basic sphere and rod nanostructures for diagnosis.

    Conclusions:

    • Single particle plasmonics provides unique insights for biomedical diagnosis.
    • Advances in synthesis and characterization enable sophisticated nanoplasmonic applications.
    • Designing single nanoparticles for single biomolecule detection will revolutionize biomedical diagnostics.