Further temperature-sensitive mutants of Escherichia coli with altered ribosomal proteins

Various alterations in ribosomal proteins were detected in forty-one mutants of E. coli isolated as temperature-sensitive mutants. Out of these, six are new classes of mutants harboring mutations in proteins S3, L5, L7 (L12), L29, L30 and L33. One of them apparently lacks protein L7 of the large subunit. These mutants together with those reported previously (Isono et al., 1976) total one hundred and one ribosomal mutants in thirty different proteins.