Related Experiment Video
Updated: Dec 13, 2025

Murine Model of Epicutaneously-Induced Immunomodulation
Published on: June 24, 2025
Acute inflammatory Demodex-induced pustulosis in an immunocompetent patient related to topical steroid use
Anthony K Guzman1, Julia K Gittler1, Bijal Amin2
1Division of Dermatology, Department of Internal Medicine, Albert Einstein College of Medicine, Bronx, NY, USA.
Abstract:
Demodex spp. mites are a common colonizer of sebaceous adult skin. Though usually clinically insignificant, demodicosis may be associated with a wide spectrum of skin diseases in immunocompetent hosts, such as erythematotelangiectatic and papulopustular rosacea, Demodex folliculorum, and blepharitis. We present a case of a healthy 9-year-old boy with an exuberant, inflammatory, Demodex-associated pustular eruption of the face, induced by the use of a high-potency topical steroid and successfully treated with oral ivermectin.
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