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Updated: Dec 13, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
[Primary cardiac tumors. Experience in 72 cases]
Roberto González L1, Claudio Toloza A2, Rodrigo Reyes M1
1Hospital Clínico Regional de Concepción "Dr. Guillermo Grant Benavente", Concepción, Chile.
Primary cardiac tumors (PCT) are rare, with myxomas being the most common. Surgical treatment offers an excellent prognosis for benign tumors, while malignant tumors have a poorer long-term survival rate.
Area of Science:
- Cardiovascular Surgery
- Cardiac Oncology
- Diagnostic Imaging
Background:
- Primary cardiac tumors (PCT) are infrequently encountered, and their clinical presentation and progression are not widely understood.
- Understanding the characteristics and outcomes of PCT is crucial for effective patient management.
Purpose of the Study:
- To delineate the key features, treatment modalities, follow-up strategies, and survival rates of patients diagnosed with primary cardiac tumors (PCT).
Main Methods:
- A retrospective review of 72 surgical procedures for PCT performed between 1984 and 2019 at a regional hospital.
- Data were compiled from surgical records, pathology databases, medical charts, and national registries.
- Analysis included patient demographics, tumor histology, location, presenting symptoms, surgical interventions, and postoperative outcomes.
Main Results:
- Myxoma (68%), papillary fibroelastoma (18%), and sarcoma (8.3%) were the predominant histological types among the 72 reviewed PCTs.
- Echocardiography was the primary diagnostic tool, identifying tumors in the left atrium (71%), aortic valve (14%), and right atrium (11%).
- Surgical resection, with or without patch repair, resulted in no immediate postoperative mortality, with a favorable long-term survival for benign tumors compared to malignant ones.
Conclusions:
- Benign neoplasms, particularly myxomas, constitute the majority of primary cardiac tumors.
- Echocardiography is the principal diagnostic method for identifying PCT.
- Surgical intervention yields excellent outcomes for benign primary cardiac tumors.
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