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Updated: Dec 13, 2025
An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
Published on: February 10, 2014
Biomechanics of Implant Fixation in Osteoporotic Bone
Kyle D Anderson1, Frank C Ko1,2, Amarjit S Virdi1,2
1Department of Cell & Molecular Medicine, Rush University Medical Center, Chicago, IL, 60612, USA.
Purpose Of Review:
The purpose of this review is to critically evaluate the current literature regarding implant fixation in osteoporotic bone.
Recent Findings:
Clinical studies have not only demonstrated the growing prevalence of osteoporosis in patients undergoing total joint replacement (TJR) but may also indicate a significant gap in screening and treatment of this comorbidity. Osteoporosis negatively impacts bone in multiple ways beyond the mere loss of bone mass, including compromising skeletal regenerative capacity, architectural deterioration, and bone matrix quality, all of which could diminish implant fixation. Recent findings both in preclinical animal models and in clinical studies indicate encouraging results for the use of osteoporosis drugs to promote implant fixation. Implant fixation in osteoporotic bone presents an increasing clinical challenge that may be benefitted by increased screening and usage of osteoporosis drugs.
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