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Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots
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Can Robots Improve Testing Capacity for SARS-CoV-2?

Kathrin Cresswell1, Sandeep Ramalingam1, Aziz Sheikh1

  • 1The University of Edinburgh, Edinburgh, United Kingdom.

Journal of Medical Internet Research
|August 1, 2020
PubMed
Summary
This summary is machine-generated.

Robotic applications for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing show promise. While patient-facing robots have limitations, laboratory-based robots offer significant safety and efficiency gains for sample processing.

Keywords:
COVID-19SARS-CoV-2infectious diseasepandemicroboticstestingvirus

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Area of Science:

  • Robotics
  • Medical Technology
  • Infectious Disease Diagnostics

Background:

  • Increasing international interest in robotic applications for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing.
  • Robots can potentially reduce transmission risks to healthcare staff and patients.

Purpose of the Study:

  • To provide an overview of recent developments in robotic applications for SARS-CoV-2 testing.
  • To assess the potential and limitations of different robotic applications in SARS-CoV-2 testing.

Main Methods:

  • Review of key recent developments in robotic applications for SARS-CoV-2 testing.
  • Analysis of the cost-effectiveness and impact on healthcare practices of patient-facing versus laboratory-based robotic systems.

Main Results:

  • Patient-facing robotic applications for SARS-CoV-2 testing have limited potential due to high costs and risks to patient-staff interactions.
  • Back-end laboratory-based robots for sample extraction and amplification show greater potential for safety and efficiency gains.
  • Integration with established laboratory processes, software, and interfaces is crucial for effective deployment.

Conclusions:

  • Deployment of laboratory-based robots for SARS-CoV-2 sample processing should be considered at scale.
  • Focusing on back-end laboratory automation offers more practical and impactful solutions for SARS-CoV-2 testing.
  • Further research into cost-effective and integrated robotic solutions for diagnostic laboratories is warranted.