[Comparative epicutaneous study on allergy to mild-fibrosing agents]

In connection with clinical observations and literature data about allergic manifestations in the oral cavity in the treatment of periodontal pockets with mild-fibrosing agents, we performed a comparative epicutaneous study on the preparations most often used in our country: Phytodont, maraslavin, zemisvet and preparation P. The method of Jadahsson and Block was used in patients with manifested periodontosis. Positive allergic tests with zemisvet and preparation P have not been established so far, whereas they were 5.71% with maraslavin and 8.57%--with phytodont. That provided grounds to recommend the fibrosing therapy in the single courses to be performed with various mild-fibrosing agents so as to reduce the possibilities of sendibilization. In the presence of data about drug allergy, the patients should be tested for allergy to the respective mild-fibrosing agents prior to the fibrosing therapy.