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Updated: Dec 13, 2025
Surface-enhanced Resonance Raman Scattering Nanoprobe Ratiometry for Detecting Microscopic Ovarian Cancer via Folate Receptor Targeting
Published on: March 25, 2019
A sandwich-type surface-enhanced Raman scattering sensor using dual aptamers and gold nanoparticles for the detection
Min Hou1, Dinggeng He, Hongchang Bu
1State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, College of Chemistry and Chemical Engineering, Hunan University, Key Laboratory for Bio-Nanotechnology and Molecular Engineering of Hunan Province, Changsha 410082, China. hedinggeng@hnu.edu.cn xiaoxiaohe@hnu.edu.cn kmwang@hnu.edu.cn.
Abstract:
A sandwich-type surface-enhanced Raman scattering (SERS) sensor using dual aptamers and gold-enhanced Raman signal probes has been successfully constructed for the detection of tumor-derived extracellular vesicles. The simple and sensitive sensor has the capability to detect tumor extracellular vesicles in 10-fold diluted human serum samples.
