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Updated: Dec 13, 2025

Portable Thermographic Screening for Detection of Acute Wallenberg's Syndrome
Published on: September 19, 2019
Wellens Syndrome without chest pain, is it possible?
1Department of Emergency Medicine, Fondazione Policlinico Gemelli, IRCCS - Università Cattolica del Sacro Cuore, Rome, Italy. mcandelli@gmail.com.
Asymptomatic patients with Wellens syndrome electrocardiogram (ECG) patterns may have severe left anterior descending artery (LAD) stenosis. Early coronary angiography is crucial for these individuals to assess potential blockages.
Area of Science:
- Cardiology
- Diagnostic Imaging
- Internal Medicine
Background:
- Wellens syndrome is a recognized electrocardiographic (ECG) pattern indicating critical proximal left anterior descending artery (LAD) stenosis.
- It typically presents with chest pain, minimal cardiac enzyme elevation, and specific ECG changes (Type A or B).
Observation:
- This report details two cases of asymptomatic individuals presenting with the Wellens ECG pattern.
- These patients experienced no chest pain or related symptoms at the time of observation.
Findings:
- Coronary angiography confirmed significant LAD stenosis in both asymptomatic patients.
- The findings highlight a potential disconnect between ECG presentation and symptomatic presentation in Wellens syndrome.
Implications:
- Asymptomatic Wellens ECG patterns warrant urgent coronary angiography due to the high likelihood of severe LAD stenosis.
- Further research is needed to determine the universal necessity of angiography for all silent Wellens presentations.
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