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Related Experiment Video

Updated: Dec 13, 2025

Microinjectrode System for Combined Drug Infusion and Electrophysiology

Microinjectrode System for Combined Drug Infusion and Electrophysiology

Published on: November 13, 2019

A Magnetically Navigated Microcannula for Subretinal Injections.

Samuel L Charreyron, Quentin Boehler, Aschraf N Danun

IEEE Transactions on Bio-Medical Engineering

|August 4, 2020

Summary

This summary is machine-generated.

This study introduces a novel robotic system using magnetic navigation for precise subretinal injections, a crucial step for new retinal disorder treatments. The flexible microcannula enhances safety and dexterity for delivering therapeutics to the retina.

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Last Updated: Dec 13, 2025

Microinjectrode System for Combined Drug Infusion and Electrophysiology

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Published on: November 13, 2019

Optimized Minimally Invasive Transscleral Subretinal Injection Technique in Mouse

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Magnetically-Assisted Remote Controlled Microcatheter Tip Deflection under Magnetic Resonance Imaging

Magnetically-Assisted Remote Controlled Microcatheter Tip Deflection under Magnetic Resonance Imaging

Published on: April 4, 2013

Area of Science:

Ophthalmology
Medical Robotics
Biomedical Engineering

Background:

Retinal disorders cause significant global vision loss.
Current treatments often require delivery to the subretinal space.
Subretinal injections are challenging and high-risk surgical procedures.

Purpose of the Study:

To develop a novel robotic system for precise subretinal injections.
To improve safety and dexterity in delivering therapeutics to the retina.
To explore an alternative to traditional robotic-assisted surgery for retinal treatments.

Main Methods:

Remote magnetic navigation to control a flexible microcannula.
Real-time cannula tracking using near-infrared tip illumination.
Semi-automatic placement with an intuitive user interface.
Ex-vivo porcine eye model for testing.

Main Results:

Successful subretinal injections were performed in ex-vivo porcine eyes.
The flexible microcannula demonstrated high dexterity and safety advantages.
Real-time tracking enabled precise cannula placement.
The system integrated microscope and optical coherence tomography visualization.

Conclusions:

Remote magnetic navigation offers a promising approach for subretinal injections.
Flexible microcannulas enhance safety and precision in retinal surgery.
This technology could advance the delivery of therapeutics for retinal disorders.