Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

8.8K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
8.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Using U-Nets to Predict the Effects of Head Motion on Simulated Specific Absorption Rate for Ultra-High Field Magnetic Resonance Imaging With Parallel Transmission.

Magnetic resonance in medicine·2026
Same author

Learning Fourier-Constrained Diffusion Bridges for MRI Reconstruction.

IEEE transactions on medical imaging·2026
Same author

DEQ-MPI: A Deep Equilibrium Reconstruction With Learned Consistency for Magnetic Particle Imaging.

IEEE transactions on medical imaging·2023
Same author

Adaptive diffusion priors for accelerated MRI reconstruction.

Medical image analysis·2023
Same author

Unsupervised Medical Image Translation With Adversarial Diffusion Models.

IEEE transactions on medical imaging·2023
Same author

TranSMS: Transformers for Super-Resolution Calibration in Magnetic Particle Imaging.

IEEE transactions on medical imaging·2022

Related Experiment Video

Updated: Dec 13, 2025

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
07:01

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

9.9K

Tomographic Field Free Line Magnetic Particle Imaging With an Open-Sided Scanner Configuration.

Can Baris Top, Alper Gungor

    IEEE Transactions on Medical Imaging
    |August 4, 2020
    PubMed
    Summary

    This study introduces the first open-sided Magnetic Particle Imaging (MPI) system using an electronically scanned field-free line (FFL) for advanced diagnostics. The novel system achieves high-resolution 3D imaging of superparamagnetic iron oxide nanoparticles (SPIONs).

    More Related Videos

    Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
    17:16

    Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

    Published on: December 9, 2010

    10.6K
    Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
    08:51

    Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

    Published on: February 19, 2021

    9.5K

    Related Experiment Videos

    Last Updated: Dec 13, 2025

    Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
    07:01

    Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

    Published on: June 9, 2016

    9.9K
    Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
    17:16

    Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

    Published on: December 9, 2010

    10.6K
    Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
    08:51

    Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

    Published on: February 19, 2021

    9.5K

    Area of Science:

    • Biomedical Engineering
    • Medical Imaging
    • Nanotechnology

    Background:

    • Superparamagnetic iron oxide nanoparticles (SPIONs) show promise for clinical diagnostics and therapies.
    • Magnetic Particle Imaging (MPI) visualizes SPION distribution using a field-free region (FFR).
    • Field-free line (FFL) scanners offer higher sensitivity and are suitable for large-area imaging compared to field-free point (FFP) scanners.

    Purpose of the Study:

    • To present the first open-sided MPI system capable of electronic FOV scanning with an FFL.
    • To demonstrate the generation of tomographic MPI images using this novel system.
    • To evaluate the system's performance in imaging phantoms with varying concentrations and stenosis.

    Main Methods:

    • Development of an open-sided MPI system with an electronically steerable FFL.
    • Implementation of a measurement-based system matrix reconstruction method minimizing l1-norm and total variation.
    • Imaging of phantom setups including varying SPION concentrations and vessel stenosis models.

    Main Results:

    • Successful electronic rotation of the FFL in the horizontal plane and 3D translation for image acquisition.
    • Generation of 2D MPI images for phantoms with iron concentrations from 11 to 770 [Formula: see text]/ml.
    • High-quality 2D imaging of vessel phantoms with up to 75% stenosis, achieving a resolution of 2.5 mm.

    Conclusions:

    • The developed open-sided MPI system with an electronically scanned FFL enables high-resolution 3D imaging.
    • This technology holds significant potential for interventional procedures and advanced SPION-based diagnostics.
    • The system demonstrates robust performance in imaging clinically relevant phantoms.