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Updated: Dec 13, 2025

A Package of Established Analytical Tools to Investigate the Solid-State Alteration of Lipid-Based Excipients
Published on: August 9, 2022
Sucrose fatty acid esters: synthesis, emulsifying capacities, biological activities and structure-property profiles
Yinglai Teng1,2, Scott G Stewart3,4, Yao-Wen Hai1
1Institute for Advanced and Applied Chemical Synthesis, Jinan University, Zhuhai, Guangdong, China.
Abstract:
The notable physical and chemical properties of sucrose fatty acid esters have prompted their use in the chemical industry, especially as surfactants, since 1939. Recently, their now well-recognized value as nutraceuticals and as additives in cosmetics has significantly increased demand for ready access to them. As such a review of current methods for the preparation of sucrose fatty acid esters by both chemical and enzymatic means is warranted and is presented here together with an account of the historical development of these compounds as surfactants (emulsifiers). The somewhat belated recognition of the antimicrobial, anticancer and insecticidal activities of sucrose esters is also discussed along with a commentary on their structure-property profiles.
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