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In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Cardiovascular CT and MRI in 2019: Review of Key Articles
Jonathan D Dodd1, Jonathon Leipsic1
1From the Department of Radiology, St. Vincent's University Hospital, Elm Park, Dublin D4, Ireland (J.D.D.); School of Medicine, University College Dublin, Dublin, Ireland (J.D.D); and Department of Radiology, University of British Columbia, St. Paul's Hospital, Vancouver, Canada (J.L.).
Insights
This review highlights key advancements in cardiac imaging, including coronary CT angiography, cardiac MRI, and AI applications. These findings offer practical insights for clinical practice and cardiovascular trials.
Area of Science:
- Cardiovascular Imaging
- Radiology
- Clinical Practice
Background:
- Cardiac imaging is increasingly vital in radiology, cardiovascular trials, and clinical guidelines.
- Recent studies have advanced the understanding and application of various cardiac imaging modalities.
Purpose of the Study:
- To summarize significant cardiac imaging findings from the past year relevant to clinical practice.
- To highlight pragmatic and scientifically valuable research in cardiovascular imaging.
Main Methods:
- Review of key articles from Radiology and high-impact clinical journals.
- Focus on meta-analyses, outcome trials, and registry data.
Main Results:
- Coronary CT angiography shows diagnostic accuracy, prognostic value of plaque features, and sex differences.
- CT is crucial for transcatheter valve replacements; MRI reveals phenotypes and prognostic utility in cardiomyopathies and Fabry disease.
- AI/ML applications, adenosine stress perfusion cardiac MRI, CT-derived fractional flow reserve, vaping effects, and whole-body MRI for metabolic syndrome were noteworthy.
Conclusions:
- Advancements in cardiac imaging offer enhanced diagnostic and prognostic capabilities.
- These findings have significant implications for patient care and cardiovascular research.
Abstract:
Cardiac imaging is becoming commonplace throughout radiology practices and is increasingly important in large-cohort prospective cardiovascular trials and in statements and guidelines. In this review, the authors summarize some of the most important imaging findings relevant to clinical practice in the past year. Key coronary CT angiography studies have included rigorous meta-analysis of its diagnostic accuracy, prognostic implications of adverse coronary plaque features, and sex differences. The value of CT for catheter-delivered valve implantation (eg, transcatheter aortic and mitral valve replacements) was further elucidated in large-cohort outcome trials. Hypertrophic cardiomyopathy registries have revealed distinct clinical and MRI phenotypes, highlighting different underlying causes, while others clarified the prognostic usefulness of MRI in hypertrophic cardiomyopathy and Fabry disease. Artificial intelligence and/or machine learning was applied to many aspects of cardiovascular imaging, while evidence of the benefits of both adenosine stress perfusion cardiac MRI and coronary CT angiography-derived fractional flow reserve from real-world trials has increased. Studies on vaping and vascular endothelial function and the whole-body MRI depiction of metabolic syndrome consequences were also noteworthy. Although this review focuses on Radiology articles, key articles from high-impact clinical journals are also included. Although not possible to detail all articles because of space limitations, the authors attempted to highlight those with the most pragmatic and scientific value.
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