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Updated: Aug 6, 2026

Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation
Published on: June 3, 2018
The Role of Preprocedural CT in Redo Transcatheter Aortic Valve Replacement: A Radiologist's Perspective
Ruurt A Jukema1,2,3,4, Ethan Levene1, John K Khoo1,2,3
1Department of Radiology, St. Paul's Hospital and University of British Columbia, 1081 Burrard St, Vancouver, BC, Canada V6Z 1Y6.
Insights
As transcatheter heart valves (THV) fail, cardiac CT imaging is crucial for assessing dysfunction mechanisms and guiding redo TAVR (transcatheter aortic valve replacement) procedures. This CT assessment differs from initial TAVR, focusing on index THV characteristics for optimal redo valve selection.
Area of Science:
- Cardiovascular Imaging
- Interventional Cardiology
Background:
- Transcatheter aortic valve replacement (TAVR) is increasingly used across all surgical risk levels.
- Patients receiving TAVR at younger ages may outlive the durability of their initial transcatheter heart valve (THV).
- THV failure necessitates reintervention, often via redo TAVR (TAV-in-TAV).
Purpose of the Study:
- To highlight the distinct role of cardiac CT in evaluating index THV failure.
- To guide the selection of the new THV type and size for redo TAVR procedures.
- To emphasize the importance of assessing commissural and coronary alignment for redo TAVR.
Main Methods:
- Cardiac CT is utilized to assess the mechanism of THV failure, differentiating between structural and nonstructural dysfunction.
- CT imaging guides the sizing and selection of the new THV for redo TAVR.
- Preprocedural CT assessment for redo TAVR considers index THV characteristics and alignment from the initial procedure.
Main Results:
- Cardiac CT effectively identifies THV dysfunction mechanisms.
- CT imaging informs optimal sizing and selection of the redo THV.
- Assessment of index THV characteristics and alignment is critical for successful redo TAVR.
Conclusions:
- Cardiac CT is indispensable for evaluating THV failure and planning redo TAVR.
- Understanding differences in CT assessment for redo TAVR is vital for procedural success.
- CT guides decisions impacting coronary access and potential leaflet modification in redo TAVR.
Abstract:
As transcatheter aortic valve replacement (TAVR) has become a viable option across all surgical risk levels, younger patients are anticipated to outlive the durability of their index transcatheter heart valve (THV). When a THV fails, cardiac CT is an important tool to assess the mechanism of THV failure and aids in the differentiation between structural and nonstructural THV dysfunction mechanisms. After the identification of the index THV dysfunction mechanism, CT guides the sizing and selection of the new THV type. While the principles of preprocedural redo TAVR (often called TAV-in-TAV) CT assessment overlap with those for patients undergoing TAVR of surgical bioprosthetic valves, the assessment is different in several ways. These differences are primarily related to the need to evaluate the characteristics of the index THV and the degree of commissural and coronary alignment achieved during the index TAVR procedure, which affect the selection of the type and size of the new THV and determine the risks of coronary obstruction and impeded future coronary access, as well as the potential for leaflet modification. Keywords: Applications-CT, CT Angiography, Transcatheter Aortic Valve Implantation/Replacement, TAVI/TAVR Supplemental material is available for this article. ©RSNA, 2026.
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