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[Morphometric determination of changes in mastocyte population in cutaneous wound granulation tissue in hypothyroid
Abstract:
The authors have done a morphometric study by determination of mastocyte population of cutaneous wound's granulation tissue of parotidectomized rats and rats which were submitted to daily administration of 25 mg of 6-propyl-2-thiouracil (hypothyroid). The animals were sacrificed after four, eight and 12 post-operative days. The results analysis permitted to observe a statistically significant diminution of mastocyte population in the hypothyroid and parotidectomized animals granulation tissue in the fourth and 12th postsurgical days.