Imaging in Primary Sjögren's Syndrome.

Area of Science:

• Rheumatology
• Radiology
• Pathology

Background:

• Primary Sjögren's syndrome (pSS) is a systemic autoimmune disorder impacting salivary and lacrimal glands, causing sicca symptoms.
• pSS diagnosis is complex due to diverse clinical presentations.
• Imaging modalities are crucial for pSS diagnosis, monitoring, and complication assessment.

Purpose of the Study:

• To review current imaging techniques for primary Sjögren's syndrome (pSS).
• To emphasize the role of salivary gland imaging in pSS diagnosis and management.
• To correlate imaging findings with histopathological changes in pSS patients.

Main Methods:

• Descriptive review of imaging techniques used in pSS.
• Focus on imaging of salivary glands in pSS.
• Linking imaging findings to salivary gland histopathology.

Main Results:

• Various imaging techniques assist in pSS diagnosis and follow-up.
• Imaging offers insights into disease activity and progression in pSS.
• Salivary gland imaging aids in diagnosing and staging pSS-associated lymphomas.

Conclusions:

• Imaging techniques are valuable tools in the diagnostic work-up of pSS.
• Salivary gland imaging plays a significant role in assessing pSS activity and progression.
• Imaging findings can be correlated with histopathological hallmarks of pSS and associated lymphomas.