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Racial and/or Ethnic and Socioeconomic Disparities of SARS-CoV-2 Infection Among Children
Monika K Goyal1,2, Joelle N Simpson3,2, Meleah D Boyle3
1Children's National Hospital, Washington, District of Columbia; and mgoyal@childrensnational.org.
Insights
Minority and low-income children experienced higher rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Addressing these disparities is crucial for controlling the pandemic
Area of Science:
- Pediatric infectious diseases
- Public health
- Epidemiology
Background:
- Racial/ethnic and socioeconomic disparities in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection rates among children are not well understood.
- Understanding these differences is critical for developing targeted interventions and mitigating health inequities.
Purpose of the Study:
- To evaluate racial/ethnic and socioeconomic disparities in SARS-CoV-2 infection rates among children.
- To assess the association between race/ethnicity, socioeconomic status, and SARS-CoV-2 infection and exposure in pediatric populations.
Main Methods:
- A cross-sectional study was conducted involving 1000 children tested for SARS-CoV-2 at a dedicated pediatric testing site.
- Bivariable and multivariable logistic regression analyses were used to examine the relationship between patient demographics (race/ethnicity, estimated median family income) and SARS-CoV-2 infection and exposure.
Main Results:
- Overall, 20.7% of children tested positive for SARS-CoV-2.
- Minority children (Hispanic and non-Hispanic Black) exhibited significantly higher infection rates compared to non-Hispanic white children.
- Children from lower socioeconomic quartiles (income) demonstrated increased rates of SARS-CoV-2 infection and reported exposure.
Conclusions:
- Racial/ethnic minority and socioeconomically disadvantaged children bear a disproportionately high burden of SARS-CoV-2 infection.
- Investigating the underlying causes of these disparities is essential for effective public health strategies and reducing infection spread.
Objectives:
To evaluate racial and/or ethnic and socioeconomic differences in rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among children.
Methods:
We performed a cross-sectional study of children tested for SARS-CoV-2 at an exclusively pediatric drive-through and walk-up SARS-CoV-2 testing site from March 21, 2020, to April 28, 2020. We performed bivariable and multivariable logistic regression to measure the association of patient race and/or ethnicity and estimated median family income (based on census block group estimates) with (1) SARS-CoV-2 infection and (2) reported exposure to SARS-CoV-2.
Results:
Of 1000 children tested for SARS-CoV-2 infection, 20.7% tested positive for SARS-CoV-2. In comparison with non-Hispanic white children (7.3%), minority children had higher rates of infection (non-Hispanic Black: 30.0%, adjusted odds ratio [aOR] 2.3 [95% confidence interval (CI) 1.2-4.4]; Hispanic: 46.4%, aOR 6.3 [95% CI 3.3-11.9]). In comparison with children in the highest median family income quartile (8.7%), infection rates were higher among children in quartile 3 (23.7%; aOR 2.6 [95% CI 1.4-4.9]), quartile 2 (27.1%; aOR 2.3 [95% CI 1.2-4.3]), and quartile 1 (37.7%; aOR 2.4 [95% CI 1.3-4.6]). Rates of reported exposure to SARS-CoV-2 also differed by race and/or ethnicity and socioeconomic status.
Conclusions:
In this large cohort of children tested for SARS-CoV-2 through a community-based testing site, racial and/or ethnic minorities and socioeconomically disadvantaged children carry the highest burden of infection. Understanding and addressing the causes of these differences are needed to mitigate disparities and limit the spread of infection.
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