Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Other Disorders of Digestive System01:30

Other Disorders of Digestive System

1.3K
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
1.3K
Gastroesophageal Reflux Disease I: Meaning and Pathophysiology01:29

Gastroesophageal Reflux Disease I: Meaning and Pathophysiology

1.1K
Gastroesophageal Reflux Disease (GERD) involves the recurrent backflow of the stomach or duodenal contents into the esophagus, leading to troublesome symptoms and potential esophageal mucosal damage. Although GERD is often referred to as a disease, it is more accurately described as a syndrome, as it encompasses a range of symptoms and complications rather than a singular pathological entity, impacting a large number of individuals as the most prevalent upper gastrointestinal problem. Roughly...
1.1K
Assessment of the Gastrointestinal System I: Subjective Data01:17

Assessment of the Gastrointestinal System I: Subjective Data

529
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
529
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

805
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
805
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

674
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
674
Factors Influencing Drug Absorption: Disease States and Pharmacology01:25

Factors Influencing Drug Absorption: Disease States and Pharmacology

1.2K
Multiple disease states can significantly influence the oral drug absorption process by affecting blood flow and the functionality of the gastrointestinal (GI) system. Various GI diseases, including conditions that alter GI motility, such as diarrhea, decreased acid secretions (achlorhydria), and infections, have been associated with reduced drug absorption.
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sun protection advice must include people with skin of colour.

International journal of cosmetic science·2026
Same author

Clinical implications of skincare: lessons from placebo-controlled dermatology trials.

Skin health and disease·2026
Same author

Cosmeceuticals in acne vulgaris: from mechanism of action to clinical application.

Skin health and disease·2026
Same author

Impact of environmental pollution on acne: a systematic review.

Skin health and disease·2026
Same author

Global consensus on the management of melanin hyperpigmentation disorders.

Journal of the European Academy of Dermatology and Venereology : JEADV·2025
Same author

Postinflammatory hyperpigmentation following cutaneous surgery in dark skin types.

Clinical and experimental dermatology·2025

Related Experiment Video

Updated: Dec 12, 2025

Author Spotlight: Exploring the Mysteries of Sichuan's Herbal Medicine in Chinese Medicine Research
03:48

Author Spotlight: Exploring the Mysteries of Sichuan's Herbal Medicine in Chinese Medicine Research

Published on: March 1, 2024

1.5K

Rosacea and the gastrointestinal system.

Tamara Searle1, Faisal R Ali2,3, Sarah Carolides4

  • 1University of Birmingham Medical School, Birmingham, UK.

The Australasian Journal of Dermatology
|August 8, 2020
PubMed
Summary

The gut microbiome influences rosacea, a skin condition causing redness and bumps. Gut dysbiosis and immune system issues are linked to rosacea, highlighting the gut-skin axis importance.

Keywords:
Helicobacter pyloriGutMicrobiomeProbioticsRosaceaSkin axisSmall Intestinal Bacterial Overgrowth

More Related Videos

Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases
07:36

Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases

Published on: July 3, 2025

477
Analyzing Oxidative Stress in Murine Intestinal Organoids using Reactive Oxygen Species-Sensitive Fluorogenic Probe
09:31

Analyzing Oxidative Stress in Murine Intestinal Organoids using Reactive Oxygen Species-Sensitive Fluorogenic Probe

Published on: September 17, 2021

4.5K

Related Experiment Videos

Last Updated: Dec 12, 2025

Author Spotlight: Exploring the Mysteries of Sichuan's Herbal Medicine in Chinese Medicine Research
03:48

Author Spotlight: Exploring the Mysteries of Sichuan's Herbal Medicine in Chinese Medicine Research

Published on: March 1, 2024

1.5K
Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases
07:36

Clinical Application of Intense Pulsed Light Therapy and Radio Frequency for Treatment of Ocular Surface Diseases

Published on: July 3, 2025

477
Analyzing Oxidative Stress in Murine Intestinal Organoids using Reactive Oxygen Species-Sensitive Fluorogenic Probe
09:31

Analyzing Oxidative Stress in Murine Intestinal Organoids using Reactive Oxygen Species-Sensitive Fluorogenic Probe

Published on: September 17, 2021

4.5K

Area of Science:

  • Dermatology
  • Gastroenterology
  • Microbiology

Background:

  • Rosacea is a prevalent inflammatory skin condition.
  • The gut-skin axis is increasingly recognized for its role in rosacea pathogenesis.
  • Gut microbiome alterations are associated with rosacea development.

Purpose of the Study:

  • To review current understanding of the gut-skin axis in rosacea.
  • To explore the role of gut microbiome dysbiosis in rosacea.
  • To investigate associations with small intestinal bacterial overgrowth and Helicobacter pylori.

Main Methods:

  • Literature review of studies on rosacea and the gut microbiome.
  • Analysis of evidence linking gut dysbiosis to skin inflammation.
  • Examination of the role of Helicobacter pylori and SIBO in rosacea.

Main Results:

  • Evidence supports the gut microbiome's role in rosacea's inflammatory response.
  • Associations found between rosacea, small intestinal bacterial overgrowth, and H. pylori.
  • Gut dysbiosis and innate immune dysregulation contribute to rosacea pathophysiology.

Conclusions:

  • The gut-skin axis is significantly implicated in rosacea.
  • Further research into the gut microbiome's role is warranted.
  • Understanding this connection may lead to more effective rosacea treatments.