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Tumor microenvironment responsive supramolecular glyco-nanovesicles based on diselenium-bridged pillar[5]arene dimer
Yang Wang1, Ming Jin, Zelong Chen
1Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling 712100, P. R. China. peiyx@nwafu.edu.cn.
Abstract:
Supramolecular glyco-nanovesicles (SeSe-(P5)2⊃Man-NH3+) based on the host-guest complex of a diselenium-bridged pillar[5]arene dimer and a mannose derivative have been successfully developed for the first time, which possessed tumor microenvironment-responsiveness and specific targetability due to their diselenium bonds and mannose units, respectively.
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