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Published on: July 4, 2021
Ischemic stroke and cerebral venous sinus thrombosis in pregnancy
Hannah J Roeder1, Jean Rodriguez Lopez1, Eliza C Miller2
1Department of Neurology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, United States.
Abstract:
Maternal ischemic stroke and cerebral venous sinus thrombosis (CVST) are dreaded complications of pregnancy and major contributors to maternal disability and mortality. This chapter summarizes the incidence and risk factors for maternal arterial ischemic stroke (AIS) and CVST and discusses the pathophysiology of maternal AIS and CVST. The diagnosis, treatment, and secondary preventive strategies for maternal stroke are also reviewed. Special populations at high risk of maternal stroke, including women with moyamoya disease, sickle cell disease, HIV, thrombophilia, and genetic cerebrovascular disorders, are highlighted.
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