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Updated: Dec 12, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Design of a BNCT irradiation room based on proton accelerator and beryllium target
Chiara Magni1, Ian Postuma2, Michele Ferrarini3
1Department of Physics, University of Pavia, V. Bassi 6, Pavia, Italy; INFN (National Institute of Nuclear Physics) Pavia, V. Bassi 6, Pavia, Italy.
Abstract:
Preliminary studies for the design of an accelerator-based BNCT clinical facility are presented. The Beam Shaping Assembly neutron activation was evaluated experimentally and with Monte Carlo simulations. The activations of patient, air and walls in the room, the absorbed doses by the patient and the in-air dose distributions were evaluated. Based on these calculations, different walls compositions were tested to optimize the environmental conditions. Borated concrete, advantageously reducing the thermal flux in the room, was proven the best choice.
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