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Association Between Fine Particulate Matter and Fatal Hemorrhagic Stroke Incidence: A Time Stratified Case-Crossover
Binxin Cai1, Tian Xia, Yifeng Qian
1Songjiang District Center for Disease Control and Prevention, Shanghai, China (Dr B Cai, Dr Lu); Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China (Dr Xia, Dr R Cai, Dr Wang); Department of Oral and Craniomaxillofacial Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai JiaoTong University School of Medicine, Shanghai, China (Dr Qian).
Objectives:
Evidence of the association between fine particulate (PM2.5, particles ≤2.5 μm in aerodynamic diameter) air pollution and fatal hemorrhagic stroke incidence is limited. This study aims to document the relationship between PM2.5 exposure and fatal hemorrhagic stroke incidence.
Methods:
The time-stratified case-crossover approach was applied for the analysis.
Results:
The mean concentration of PM2.5 is 75.33 μg/m. Fatal hemorrhagic stroke incidence was significantly associated with PM2.5 exposure. Exposure to PM2.5 led to a 5% (2%-9%) and 5% (1%-10%) increase in fatal hemorrhagic stroke incidence in lag2 and lag03 respectively. An increased risk was observed especially in men and subjects with hypertension.
Conclusions:
This study provides evidence for the association between PM2.5 exposure and fatal hemorrhagic stroke incidence. Men and subjects with hypertension have increased risks, overweight may further increase their susceptibility to PM2.5 exposure related hemorrhagic stroke.
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