Related Experiment Video
Updated: Dec 12, 2025

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Cognitive Impairment Evaluation and Management
Lauren McCollum1, Jason Karlawish2
1Penn Memory Center, University of Pennsylvania, Philadelphia, PA, USA; Ralston House, Penn Memory Center, ATTN: Maria Crudele, 3615 Chestnut Street, Philadelphia, PA 19104-2612, USA.
A systematic approach, including informant interviews and mental status exams, is crucial for evaluating cognitive impairment. This process guides diagnosis and informs essential treatment strategies for affected individuals.
Area of Science:
- Neurology
- Geriatrics
- Psychiatry
Background:
- Cognitive impairment is a growing concern in clinical practice.
- Accurate diagnosis is essential for effective patient management.
Purpose of the Study:
- To outline a systematic approach for evaluating cognitive impairment.
- To emphasize the importance of informant interviews and mental status examinations.
- To guide subsequent diagnostic work-up and treatment planning.
Main Methods:
- Systematic clinical evaluation.
- Informant interviews to gather collateral information.
- Thorough mental status examination to assess cognitive domains.
- Differential diagnosis based on impairment patterns.
Main Results:
- A structured approach identifies functional impairments and affected cognitive domains.
- The pattern of cognitive deficits guides the differential diagnosis.
- Diagnostic work-up is tailored based on initial findings.
Conclusions:
- A systematic evaluation is fundamental for diagnosing cognitive impairment.
- Interventions should address symptoms, with environmental, psychological, and behavioral strategies being key.
- Early and accurate diagnosis leads to more effective management plans.
Related Concept Videos
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
Cognitive Development During Adulthood
Dementia
The progression of dementia is generally gradual....
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
Alzheimer's Disease: Treatment
Cognitive Therapy

