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Two Cases of SARS-CoV-2 Infection in Pediatric Oncohematologic Patients in Spain

Iñigo Pérez-Heras1, Verónica Fernandez-Escobar2, María Del Pozo-Carlavilla2

  • 1From the Paediatric Haematology and Oncology Unit, Hospital Virgen de la Salud, Toledo, Madrid, Spain.

The Pediatric Infectious Disease Journal
|August 11, 2020
PubMed

Insights

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pediatric cancer patients often presents mildly. Further research is needed to confirm these findings in larger pediatric oncology populations.

Area of Science:

  • Pediatric Oncology
  • Infectious Diseases
  • Hematology

Background:

  • The global spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) raises concerns for immunocompromised populations, particularly pediatric cancer patients.
  • Understanding the clinical course of SARS-CoV-2 infection in this vulnerable group is crucial for appropriate management and public health strategies.

Observation:

  • This study reports on two pediatric cancer patients diagnosed with SARS-CoV-2 infection.
  • Both patients exhibited mild disease presentation without respiratory symptoms.

Findings:

  • One patient experienced diarrhea, potentially linked to lopinavir/ritonavir treatment.
  • The observed mild disease course and good outcomes in these pediatric cancer patients warrant further investigation.

Implications:

  • Pediatric cancer patients might experience less severe SARS-CoV-2 disease compared to adults.
  • Larger-scale studies are necessary to establish definitive conclusions regarding SARS-CoV-2 outcomes in pediatric oncology.
  • This highlights the need for tailored monitoring and treatment protocols for immunocompromised children during viral outbreaks.

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