Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chest Physiotherapy01:24

Chest Physiotherapy

1.2K
Chest Physiotherapy (CPT) is a therapeutic technique used in respiratory care to improve ventilation, clear bronchial secretions, and enhance the efficiency of respiratory muscles. This therapy includes three primary procedures: postural drainage, percussion, and vibration. It can be performed on spontaneously breathing patients and those who are intubated and mechanically ventilated.
Purpose
CPT is primarily used for patients with excessive bronchial secretions who have difficulty clearing...
1.2K
Ventilatory Modes01:14

Ventilatory Modes

975
Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
975
Factors Affecting Pulmonary Ventilation01:19

Factors Affecting Pulmonary Ventilation

2.5K
Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
2.5K
Mechanical Ventilation I: Indication and Settings01:29

Mechanical Ventilation I: Indication and Settings

2.1K
Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
2.1K
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

409
Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
409
Pulmonary Ventilation: Inhalation01:24

Pulmonary Ventilation: Inhalation

6.8K
Pulmonary ventilation is a vital process that ensures the exchange of oxygen and carbon dioxide in the lungs. It refers to the movement of air into and out of the lungs, enabling the body to obtain oxygen and remove waste carbon dioxide. In this article, we will explore the intricacies of pulmonary ventilation, including its underlying principles, mechanisms, and the interplay of pressures within the respiratory system.
Boyle's law becomes particularly pertinent when examining respiratory...
6.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of Baydur Ratio Correction on the Reliability of Esophageal Pressure Measurement.

Journal of applied physiology (Bethesda, Md. : 1985)·2026
Same author

Obesity: biomechanical implications for mechanical ventilation.

Critical care (London, England)·2026
Same author

Lung Superimposed Pressure in Pediatric Acute Respiratory Distress Syndrome: Single-Center Study, 2014-2024.

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·2026
Same author

Survival Heterogeneity in U.S. Hospice Patients: A Retrospective Cohort Study.

The American journal of hospice & palliative care·2026
Same author

Sex-related differences in lung injury distribution and outcomes in COVID-19 acute respiratory failure: insights from the CT-COVID19 multicenter study group.

Intensive care medicine experimental·2026
Same author

Adaptive Riemannian optimization for multi-scale diffeomorphic matching.

Nature communications·2026

Related Experiment Video

Updated: Dec 12, 2025

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging
10:44

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Published on: June 21, 2024

947

Positional Therapy and Regional Pulmonary Ventilation.

Yi Xin, Maurizio Cereda, Hooman Hamedani

    Anesthesiology
    |August 11, 2020
    PubMed
    Summary
    This summary is machine-generated.

    Prone ventilation improves lung inflation, particularly in the dorsal and caudal regions. This study in pigs shows localized lung recruitment effects that may explain clinical benefits.

    More Related Videos

    Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent
    08:26

    Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent

    Published on: June 5, 2019

    6.8K
    Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
    08:17

    Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

    Published on: June 7, 2015

    16.1K

    Related Experiment Videos

    Last Updated: Dec 12, 2025

    Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging
    10:44

    Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

    Published on: June 21, 2024

    947
    Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent
    08:26

    Quantitative Mapping of Specific Ventilation in the Human Lung using Proton Magnetic Resonance Imaging and Oxygen as a Contrast Agent

    Published on: June 5, 2019

    6.8K
    Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
    08:17

    Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

    Published on: June 7, 2015

    16.1K

    Area of Science:

    • Physiology
    • Medical Imaging
    • Respiratory Medicine

    Background:

    • Prone ventilation is known to redistribute lung inflation along gravitational forces.
    • Localized, non-gravitational effects of body positioning on lung inflation are less understood.
    • This study reanalyzed existing large animal data to investigate these effects.

    Purpose of the Study:

    • To test the hypothesis that lung inflation improvements from prone positioning follow both gravitational and non-gravitational distributions.
    • To characterize regional lung tissue responses to prone ventilation.

    Main Methods:

    • Computed tomography (CT) scans of mechanically ventilated pigs were analyzed before and after induced lung injury.
    • CT scans were acquired at two levels of positive end-expiratory pressure (PEEP) in both prone and supine positions.
    • Lung tissue was computationally clustered based on changes in density and dimensions to identify deflation, limited response, and reinflation.

    Main Results:

    • Three distinct tissue clusters (deflation, limited response, reinflation) were identified, with reinflation comprising approximately 23% of lung mass.
    • Reinflation was predominantly observed in the dorsal (86.4%) and caudal (63.4%) regions of the lung.
    • Prone positioning recruited significant lung tissue, primarily in the caudal regions, with greater recruitment at lower PEEP after injury.

    Conclusions:

    • Prone ventilation during mechanical ventilation leads to lung reinflation and recruitment primarily in the dorso-caudal lung regions.
    • The localized effects of prone positioning in these specific lung areas likely contribute to its clinical effectiveness.
    • Understanding these regional responses is crucial for optimizing prone ventilation strategies.