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Updated: Dec 12, 2025

Identifying Dysregulated Genes Induced by Kaposi's Sarcoma-associated Herpesvirus KSHV
Published on: September 14, 2010
[IAssociation between Kaposi´s sarcoma and multiple myeloma: is it caused by HHV-8?]
Sophia Kahouli1,2, Hafid Zahid2,3, Majid Benkirane2,4
1Laboratoire de Recherche et d´Analyses Médicales de la Fraternelle de la Gendarmerie Royale, Rabat, Maroc.
Abstract:
Kaposi´s sarcoma is a tumor characterized by purple or brownish lesions affecting the skin. It is most commonly associated with human herpes virus type 8 (HHV-8) infection and may be secondary to malignant hemopathy, including lymphomas. We here report a new case of a very rare combination: Kaposi´s disease-multiple myeloma. The study involved Mr. aged 67 years, treated for Kaposi´s disease in the Department of Dermatology. Serological test for HHV-8 was positive; it was associated with stage I multiple myeloma IgG Lambda with a poor prognosis. We here report this 21st case of Kaposi-Kahler in order to highlight Kaposi-human herpes 8 virus variant involved in the pathophysiology of multiple myeloma. More studies are needed in order to establish this exceptional link.
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