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Published on: January 19, 2024
Portuguese Consensus on Diagnosis, Treatment, and Management of Anemia in Pediatric Inflammatory Bowel Disease
Ana Isabel Lopes1,2, Sara Azevedo2, José Cabral3
1Faculty of Medicine of the University of Lisbon, Lisbon Academic Medical Centre (CAML), Lisbon, Portugal.
Insights
Anemia is common in pediatric inflammatory bowel disease (IBD). This consensus provides the first national guidelines for diagnosing and managing iron deficiency anemia in children with IBD, improving patient care.
Area of Science:
- Gastroenterology
- Pediatrics
- Hematology
Background:
- Anemia is a frequent complication in pediatric inflammatory bowel disease (IBD).
- Iron deficiency is the primary cause of anemia in IBD patients.
- Anemia significantly impacts patients' quality of life and requires prompt management.
Purpose of the Study:
- To establish the first national consensus on managing anemia in pediatric IBD.
- To provide evidence-based recommendations for diagnosing and treating iron deficiency and iron-deficiency anemia in this population.
Main Methods:
- Development of national consensus guidelines.
- Review of existing evidence on anemia in pediatric IBD.
- Formulation of clinical recommendations for diagnosis and treatment.
Main Results:
- The consensus addresses the scarcity of specific guidelines for pediatric IBD anemia.
- It emphasizes an active treatment approach, including intravenous iron formulations.
- Recommendations are tailored for the pediatric population.
Conclusions:
- This consensus provides crucial guidance for clinicians managing anemia in pediatric IBD.
- It aims to improve the timely diagnosis and effective treatment of iron deficiency anemia.
- Implementation of these recommendations is expected to enhance clinical practice and patient outcomes.
Abstract:
Anemia is a common extraintestinal manifestation of inflammatory bowel disease (IBD), both in pediatric and in adult patients. Iron deficiency is the main cause of anemia in patients with IBD. Anemia is a clinically relevant comorbidity, with impact on patients' quality of life and it should be timely diagnosed and adequately treated. Currently, an active treatment approach is the recommended strategy, with evidence showing efficacy and safety of intravenous iron formulations. However, evidence in pediatric age remains scarce and no clinical recommendations exist for the diagnosis and treatment of this particular age group. The present document represents the first national consensus on the management of anemia in pediatric IBD and is therefore particularly relevant. The authors anticipate that the proposed recommendations will be useful in daily clinical practice for diagnosing and managing iron deficiency and iron-deficiency anemia in the pediatric population with IBD.
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