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Updated: Dec 12, 2025

Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
Physical Function Assessment in Older Hemodialysis Patients.
Rasheeda K Hall1,2,3,4, Jeanette Rutledge3, Alison Luciano4
1Renal Section, Durham Veterans Affairs Healthcare System, Durham, NC.
Repeated physical function tests like SPPB and grip strength are appropriate for older adults on dialysis. These assessments help track changes in mobility and daily living activities over time.
Area of Science:
- Gerontology
- Nephrology
- Rehabilitation Medicine
Background:
- Physical function is crucial for independence in older adults.
- Routine physical function assessment is lacking in older adults undergoing dialysis.
- Maintaining physical function is vital for quality of life in this population.
Purpose of the Study:
- To evaluate the appropriateness of repeated physical function measurements in older adults receiving dialysis.
- To assess the feasibility and utility of the Short Physical Performance Battery (SPPB), handgrip strength, and activities of daily living (ADLs) in this cohort.
Main Methods:
- Prospective study involving 37 community-dwelling adults aged 65+ receiving in-center hemodialysis.
- Measurements included SPPB, handgrip strength, and Katz and Lawton ADLs at baseline and 3-month intervals up to 6 months.
- Evaluated completion rates, test effects, and clinically meaningful changes.
Main Results:
- 37 participants were enrolled (67% enrollment rate); retention was 74% at 6 months.
- Measurements were well-tolerated, with minimal participant non-completion.
- Clinically meaningful changes in SPPB, grip strength, and gait speed were observed at 3-month intervals for some participants.
Conclusions:
- The Short Physical Performance Battery (SPPB), handgrip strength, and gait speed are appropriate for interval physical function assessment in older adults on hemodialysis.
- These measures can effectively track changes in physical function over time in this population.
- Further research should address geographic and ethnic diversity.
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