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Updated EORTC QLQ-C30 general population norm data for Germany.

Sandra Nolte1, Annika Waldmann2, Gregor Liegl3

  • 1Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Medical Department, Division of Psychosomatic Medicine, Berlin, Germany; School of Health and Social Development, Faculty of Health, Deakin University, Burwood, VIC, Australia.

European Journal of Cancer (Oxford, England : 1990)
|August 11, 2020
PubMed
Summary
This summary is machine-generated.

Updated norm data for the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life questionnaire, QLQ-C30, in Germany is now available. This data helps interpret patient-reported outcomes for cancer patients by comparing them to the general population.

Keywords:
EORTC QLQ-C30General populationGermanyNorm dataNormative dataPatient-reported outcomesQuality of lifeSelf-reportSurvey

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Area of Science:

  • Health outcomes research
  • Psychometrics
  • Oncology

Background:

  • The European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life questionnaire, QLQ-C30, is a key patient-reported outcome (PRO) instrument.
  • Accurate interpretation of PRO data necessitates comparison with general population norm data.
  • Previous norm data for the EORTC QLQ-C30 in Germany may be outdated.

Purpose of the Study:

  • To present updated general population norm data for the EORTC QLQ-C30 specifically for Germany.
  • To provide a contemporary reference dataset for researchers and clinicians.
  • To facilitate more accurate health-related quality of life assessments in cancer patients.

Main Methods:

  • Data collected via an online survey as part of a larger international study.
  • Linear transformation of raw EORTC QLQ-C30 scores.
  • Data weighted using United Nations population distribution statistics.
  • Norm data presented stratified by age and sex/age.

Main Results:

  • 1006 German participants completed the survey.
  • Observed sex differences: men generally scored higher on function scales and lower on symptom scales compared to women.
  • Age-related patterns were mixed: older individuals showed lower physical/role functioning but higher emotional functioning.
  • Symptom severity varied across age groups, with some symptoms increasing and others decreasing with age.

Conclusions:

  • This study provides updated EORTC QLQ-C30 general population norm data for Germany.
  • The presented data are suitable for direct comparison with EORTC QLQ-C30 data from cancer patient populations.
  • These updated norms enhance the interpretability of quality of life assessments in German cancer patients.