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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
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Radiation therapy strategies for skull-base malignancies
J D Palmer1,2, M E Gamez1, K Ranta1
1Department of Radiation Oncology, The James Cancer Hospital at the Ohio State University Wexner Medical Center, Columbus, OH, USA.
Journal of Neuro-Oncology
|August 14, 2020
Summary
Radiation therapy is crucial for managing skull base tumors. Recent advancements enhance the risk/benefit ratio for radiotherapy in treating these complex malignancies.
Area of Science:
- Oncology
- Radiation Oncology
- Neurosurgery
Background:
- Skull base malignancies require evolving management strategies.
- Multimodality care, including surgery, radiation, and systemic agents, is common.
- Advances in surgical techniques and systemic therapies are ongoing.
Purpose of the Study:
- To review the management of common skull base pathologies.
- To focus on the radiotherapeutic aspects of care for these tumors.
- To highlight the role of multimodality therapy.
Main Methods:
- Literature review of skull base tumor management.
- Detailed discussion of radiotherapeutic approaches.
- Synthesis of outcomes from various treatment strategies.
Main Results:
- Technological advancements have diversified radiation therapy strategies.
- Various treatment modalities are employed for skull base malignancies.
- Outcomes associated with different therapeutic approaches are summarized.
Conclusions:
- Radiation treatment is a critical component in managing skull base tumors.
- Recent advancements improve the risk/benefit profile of radiotherapy.
- Continued innovation enhances patient care for skull base malignancies.

