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Updated: Dec 12, 2025

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
Published on: May 26, 2019
Zinc Hydride-Catalyzed Hydrofuntionalization of Ketones
Rajata Kumar Sahoo1, Mamata Mahato1, Achintya Jana2
1School of Chemical Sciences, National Institute of Science Education and Research (NISER), Homi Bhabha National Institute (HBNI), Bhubaneswar 752 050, India.
Abstract:
Three new dimeric bis-guanidinate zinc(II) alkyl, halide, and hydride complexes [LZnEt] (1), [LZnI] (2) and [LZnH] (3) were prepared. Compound 3 was successfully employed for the hydrosilylation and hydroboration of a vast number of ketones. The catalytic performance of 3 in the hydroboration of acetophenone exhibits a turnover frequency, reaching up to 5800 h-1, outperforming that of reported zinc hydride catalysts. Notably, both intra- and intermolecular chemoselective hydrosilylation and hydroboration reactions have been investigated.
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