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Probiotics and Covid-19
Benedetta Bottari1, Vincenzo Castellone1, Erasmo Neviani1
1Department of food and drug, University of Parma, Parma, Italy.
Probiotics may help manage coronavirus disease 2019 (COVID-19) by addressing gut microbiota dysbiosis and leveraging the lung-gut axis. This review compiles current information on probiotics for COVID-19 prevention and treatment.
Area of Science:
- Microbiology
- Immunology
- Gastroenterology
Background:
- The rapid global spread of COVID-19 necessitates exploring novel therapeutic strategies.
- Probiotics have been suggested for COVID-19 based on indirect evidence and their known effects on viral respiratory infections.
- Emerging research highlights a "lung-gut axis," linking gut health to respiratory conditions.
Purpose of the Study:
- To consolidate existing research on the role of probiotics in COVID-19.
- To provide a foundation for future investigations into probiotic interventions for COVID-19.
Main Methods:
- Systematic review of current literature on probiotics and COVID-19.
- Analysis of studies investigating gut microbiota dysbiosis in COVID-19 patients.
- Examination of the lung-gut axis in the context of viral respiratory diseases.
Main Results:
- COVID-19 is associated with intestinal microbiota dysbiosis.
- Probiotics show potential efficacy in managing viral respiratory tract infections.
- The lung-gut axis provides a theoretical basis for probiotic use in COVID-19.
Conclusions:
- Probiotic administration is a potential therapeutic avenue for COVID-19.
- Modulating gut microbiota may be a viable strategy for COVID-19 prevention and treatment.
- Further research is needed to elucidate the specific roles and efficacy of probiotics in severe COVID-19.
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